Feed Planet Magazine Issue-Sayı: 34 January - Ocak 2022

64 ARTICLE • MAKALE FEED PLANET / JANUARY 2022 • OCAK 2022 health of the host. Epithelial physical barrier damage and immunological barrier damage are usually related to bac- terial translocation during a pathogenic infection. (Wang et al., 2018) It is also suggested that C9 has the capac- ity to induce the expression of pBD (porcine ß- defensins) genes in some cells, including the pBD-1 (that plays a potential role in surveillance and maintenance of a homeostatic state of gut microbiota on the mucosal epithelium) and pBD-2 expression (that likely inhibits patho- genic bacteria). (Wang et al., 2018) TRIAL REPORT These experiments were carried out to show the efficacy and corrosivity of Form-ad Plus and Form-ad Plus P (synergic blend of short and medium chain fatty acids and essential oils), Salmocid-F (formaldehyde-based product) and two competitors: blend 1, a mixture of free organic acids (formic acid 75 % and propionic acid 25 %) and Blend 2, a mixture of free or- ganic acid (formic acid 75 %) and ammonium formiate 25 %. In order to analyse the bactericidal efficacy of Form-ad Plus and Form-ad Plus P, we analysed the % of reduction in Salmonella Tiphymurium (103 cfu/g) of Form-ad Plus, Form-ad Plus P and Salmocid-F at a dosage of 1 kg/T compared to blends 1 and 2 of organic acids at a normal dos- age of 3 kg/T. sağlığına faydalıdır. Epitelyal fiziksel bariyer hasarı ve immünolojik bariyer hasarı, genellikle patojenik bir en- feksiyon sırasında bakteriyel translokasyon ile ilgilidir. (Wang ve arkadaşları, 2018) Ayrıca C9'un bazı hücrelerde pBD-1 (mukozal epitel üzerinde bağırsak mikrobiyotasının ho- meostatik durumunun gözetiminde ve korunma- sında potansiyel bir rol oynar) ve pBD-2 ifadesi (muhtemelen patojenik bakterileri inhibe eder) dahil olmak üzere pBD (domuz ß-defensinleri) genlerinin ifadesini indükleme kapasitesine sa- hip olduğu da ileri sürülmektedir. (Wang ve arka- daşları, 2018) DENEY RAPORU Bu deneyler, Form-ad Plus ve Form-ad Plus P (kısa ve orta zincirli yağ asitleri ve esansiyel yağ- ların sinerjik karışımı), Salmocid-F (formaldehit bazlı ürün) ve iki rakibin etkinliğini ve aşındırıcılı- ğını göstermek için yapılmıştır: karışım 1, serbest organik asitlerin bir karışımı (%75 formik asit ve %25 propiyonik asit) ve Karışım 2, serbest orga- nik asit (%75 formik asit) ve %25 amonyum format karışımı. Form-ad Plus has the same effect than the formalde- hyde-based product. Even at one-third dose, Form-ad Plus and Form-ad Plus P show higher bactericidal effect than blends 1 and 2. In order to analyse corrosivity, we conducted a corro- sion experiment, whereby test strips were immersed in different liquid solutions. Two parameters were analysed for corrosivity: test weight loss (%) and corrosion speed (mm/year). It should be highlighted the low corrosivity of these Adiveter products compared to other products based on free organic acids. This allows for safe handling and prevents the product from corroding the feed mill equip- ment and facilities, making them available for using dur- ing feed processing. We conclude that the high efficacy of Form-ad Plus and Form-ad Plus P are effective non-corrosive alternative solutions to formaldehyde-based products.